At ProteinQure, we are building a computational platform for design of protein therapeutics. Our mission is to help to create a world where drugs are engineered, not discovered.
We work on treatments for cancer, diabetes, asthma, and cardiovascular diseases, among others, and partner with industry leaders in drug discovery to generate novel therapeutics outside of the conventional chemical space.
Our technology combines computational biophysical models with statistical and machine learning approaches to enable us to search across vast spaces of protein therapeutics.
We build and deploy these computational modules using a scalable cloud computing infrastructure and complement their predictions with results from wet lab experiments.
Responsibilities : Develop novel drug candidates using our computational protein design platform with academic and industry partners Execution of protein design workflows (structure and property prediction) Data analysis and visualization for reports / presentations, delivery to partners Orchestrate platform validation for retrospective and prospective applications (may involve close interaction with experimental biologists at ProteinQure / CRO) Summarize and disseminate research on drug discovery targets, therapeutic modalities, and computational methodologies, to guide internal drug discovery and software development.
Work side-by-side with chemists, biologists, computer scientists, and software developers to develop new methods for protein design Assist in the collection / curation of biological datasets (sequence, structure, function data) for machine learning initiatives Identification of platform limitations and development of research strategies to resolve these issues.
Requirements : PhD (or 2+ years experience) in Biochemistry, Bioinformatics, Biophysics or similar field Comfort explaining technical concepts to a diverse audience Peer-reviewed publications on protein engineering, design, structure and function OR Case studies from time in industry Nice to haves : Experience with molecular modelling software (Rosetta, BioLuminate, MOE) Confidence with molecular visualization software (PyMol, Chimera, VMD) Scripting experience (Python) and knowledge of biology data formats (PDB) Experience with biophysical experiments (NMR, EPR, FRET, X-ray crystallography, etc.
or measuring protein-protein interactions (SPR, ITC, phage display) Powered by JazzHR
Computational Structural Biologist
Responsibilities: Develop novel drug candidates using our computational protein design platform with academic and industry partners Execution of protein design workflows (structure and property prediction) Data analysis and visualization for reports/presentations, delivery to partners Orchestrate pl...
310T Mechanic / Apprentice (Truck and Coach Technician)
GFL Environmental is looking for a 310T Truck & Coach Technicians (Fully licensed and/or Apprentice) to join our growing solids team out of our Toronto and Stoney Creek, Hamilton locations. The 310T Truck & Coach Technician will be primarily responsible for preventive maintenance services; i...
Laboratory Technician (Weekend, Part-Time) - Eurofins Experchem Laboratories, Inc.
The Laboratory Technician I receives sufficient authority from and is accountable to the Laboratory Supervisor or an appointed designate for the successful completion of assigned duties and responsibilities. It is also one of the global independent market leaders in certain testing and laboratory se...
Sr. Research Scientist (Polymer & Bioconjugate Chemistry)
Research Scientist (Polymer & Bioconjugate Chemistry). Research Scientist (Polymer & Bioconjugate Chemistry). As needed, write and submit original research papers to peer-reviewed journals, and/or present posters and oral presentations at research conferences. Standard BioTools Canada is looking for...
Project Controls Manager
Overall responsibility for Project Controls compliance on Projects to the AtkinsRéalis project execution standards. Lead in establishing and maintaining the project’s integrated Project Controls systems and oversee the setting and updating of the project cost and schedule databases. Support Project ...
Research Assistant
Manage day-to-day tracking of patient progress and data in ongoing research studies. Support with the creation and quality control of research source documents. Prepare research and participant binders, as required. Attend regularly scheduled Data Science team meetings and research training and meet...
Staff Environmental Scientist
This office and field position will be working with an on-site team to help plan, select, coordinate and implement scientific and environmental services to fully address the scope of work on environmental remediation and hazardous waste management projects in accordance with Company standards, regul...
disaster restoration technician
No degree, certificate or diploma.Load, unload and transport construction materials.Erect and dismantle concrete forms, scaffolding, ramps, catwalks shoring and barricades.Mix, pour and spread materials such as concrete and asphalt.Assist in demolishing buildings.Clean up chemical spills and other c...
Research Assistant 1 - Campbell Family Mental Health Research Institute
The Laboratory of Behavioural Neuroendocrinology and the NDA at the Centre for Addiction and Mental Health are seeking a casual Research Assistant 1 to join our team reporting to the lab manager and research program manager within the group. You will be part of a diverse and growing research team th...
Project Manager
The ideal candidate will oversee project priorities and milestones, working closely with the senior leadership team, field operations, clients, and other key stakeholders to ensure the successful completion of each project. Lead and develop project management processes and methods for each project, ...