Lead Clinical Research Associate

• Coordinates investigator/ site feasibility and identification process as well as study startup.
• Monitors project timelines and patient enrollment implements respective corrective and preventive measures.
• Reviews monitoring visit reports for all visit types and ensures reporting compliance of the Monitors in the region.
• Manages Monitors in the query resolution process including Central Monitoring observations.
• Coordinates safety information flow and protocol/process deviation reporting.
• Performs clinical supplies management with vendors on a country and regional level.
• Ensures study-specific and corporate tracking systems are updated in a timely manner.
• Acts as the main communication line between Monitor Site Management Associate Regional Project Lead and/ Project Manager.
• Coordinates planning of supervised monitoring visits and conducts the visits.
• Manages the project team in site contracting and payments.
• Leads project team calls on a country level as well as provides status updates and reports to Regional Lead/ Project Manager.
• Ensures ongoing evaluation of data integrity and compliance at a country/regional level.
• Conducts site audit preparation visits may participate in site audits and coordinates resolution of site audit findings on a country/regional level.
• Oversees project team in CAPA development and implementation.
• Coordinates project team in process deviations review management and reporting.
• Conducts initial training and authorization monitoring visits for Monitors and acts as a mentor for newly promoted Lead CRAs.
• Provides project-specific training and prepares training materials for the project team under supervision of a Project Manager and Regional Project Lead.
• Delivers trainings and presentations at Investigator Meetings.
• Prepares conducts and reports site selection initiation routine monitoring and closeout visits.
• Ensures that subject recruitment targets and project timelines are properly defined communicated recorded and met at site level.
• Ensures accurate and timely information flow with trial sites on Adverse Events and protocol/process deviations.
• Supervises source data verification and follows up on data queries at site level in the country/region; reviews and manages study risks on a site level.
• Ensures proper handling use accountability reconciliation and return of all Investigational Product(s) and clinical study supplies on a country/region level.
• Reviews essential study documents and supervises reconciliation of study Investigator Site File (ISF) / TMF at site level and country/region level.
• Ensures data integrity and compliance at a site level.
• Supervises Site Management Associates in the flow of documents and laboratory supplies between the site and the Central/ Regional Lab/ Central Reviewer.
• Conducts project-specific training of site Investigators.
• Supports preparation of draft regulatory and ethics committee submission packages.

Qualifications :

• Relevant educational background such as MD MPharm RN or College/University degree in Life Sciences or an equivalent combination of education training and experience.
• Minimum of 4 years site monitoring experience with participation in global clinical projects as a Lead Monitor or equivalent qualification level.
• Must have prior experience monitoring or managing sites and CRAs with knowledge of US and Canadian regulatory guidelines and practices.
• Experience with all types of monitoring visits in Phases I-III.
• Strong experience in Oncology preferred.
• Experience in CAR-T Therapy or other types of Cell Therapy Gene Therapy Radiation Therapy or Radiopharmaceuticals or Nuclear Medicine is preferred.
• Strong experience in GI (Chrons Ulcerative Colitis IBS) preferred.
• Full working proficiency in English.
• Proficiency in MS Office applications.
• Ability to plan multitask and work in a dynamic team environment.
• Excellent Communication collaboration and problem-solving skills.
• Ability to travel up to 65% (depending on project needs).
• Valid drivers license (if applicable).

Additional Information :

Advance your career in clinical research coordinating a variety of tasks and learning new things while growing with a rapid growing company that puts its people first.

Remote Work :

Yes

Employment Type :

Full-time

Experience: years
Vacancy: 1