Ap Jobs in London, ON

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

Union : Non-Union

Site : Princess Margaret Cancer Centre

Department : Research

Reports to : Principal Investigators, Dr. Mohammad Mazhab-Jafari and Dr. Thomas Kislinger

Work Model : On site

Hours : 37.5 hours per week

Salary : $53,303 - $70,000 Annually (To commensurate with experience and consistent with UHN compensation policy)

Shifts : Day

Status : Temporary Full-time

Closing Date : March 31, 2025

Position summary :

The Princess Margaret Cancer Centre, a world-leading cancer research institution, invites applications for a Postdoctoral Researcher position. The laboratories of Thomas Kislinger and Mohammad Mazhab-Jafari are seeking a highly motivated and skilled scientist with expertise in mass spectrometry to join our cutting-edge research program. This position offers the opportunity to work at the forefront of cancer research, exploring the intricate mechanisms of protein interactions and post-translational modifications in cancer biology.

The successful candidate will lead a project focused on studying fatty acid synthase (FASN) protein interactions and post-translational modifications (PTMs) across diverse cancer cell lines. Utilizing advanced affinity-purification mass spectrometry (AP-MS) techniques and cryo-electron microscopy (cryoEM), the project aims to provide deep insights into the role of FASN in cancer. The candidate will have access to state-of-the-art mass spectrometry and cryoEM instrumentation and will receive comprehensive training in these cutting-edge technologies.

Duties :

• Will be responsible for growing and maintaining cancer cell lines, conducting affinity-purification experiments, and performing mass spectrometry analyses to characterize protein interactions and modifications.
• Will analyze complex datasets to identify key biological insights (e.g., identify PTMs from AP-MS data).
• Collaborate with multidisciplinary teams to integrate findings.
• Prepare high-quality manuscripts for publication in leading scientific journals.
• Participate in the mentoring of junior lab members.
• Additional responsibilities include presenting research findings at conferences.

Qualifications

Additional Information

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.

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