Researcher Jobs in Toronto, ON

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

Union : Non-Union

Site : Princess Margaret Cancer Research Tower (PMCRT)

Reports to : Principal Investigator, Dr. Cheryl Arrowsmith

Work Model : On-Site

Grade : VE : 01

Hours : 37.5 hours per week

Salary : $55,000 - $65,000 Annually (To commensurate with experience and consistent with UHN compensation policy)

Shifts : Monday - Friday

Status : Temporary Full-time

Closing Date : April 30, 2025

Position Summary

The successful candidate will join a vibrant multi-disciplinary academic research group consisting of biochemists, structure biologists, cell biologists, and computational and medicinal chemists. In collaboration with a multi-disciplinary team at the Structural Genomics Consortium (SGC) at the University of Toronto to develop chemical probes for novel targets of interest. This project is part of the Acceleration Consortium's ‘self-driving lab’ (SDL) research to accelerate materials and drug discovery assisted by AI and automation. The position will involve helping to build a ‘hit to lead’ SDL using parallel high throughput synthesis of novel small molecules that will be tested in automated high throughput biological / biophysical assays of the target protein conducted within the Structural Genomics Consortium and guided by AI and automation specialists in the Acceleration Consortium.

Duties

• Work in collaboration with the team to develop chemical probes and drug candidates
• Synthesize compounds using automated instruments and manually to improve the profiles of the compounds
• Characterize synthesized compounds using a variety of techniques, such as HPLC / MS, NMR etc.
• Design synthetic routes for the compounds of interest
• Familiarize with automated instruments and utilize them for making a library of compounds
• Familiarize with the relevant literature
• Record and document all the experiments clearly
• Summarize the results in the reports and present to internal and external meetings
• Maintain a safe lab environment according to established health and safety protocols

Qualifications

Additional Information

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.

J-18808-Ljbffr