Research and development Jobs in Burlington, ON

Fusion Pharmaceuticals, a member of the AstraZeneca Group , is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion's clinical portfolio includes : FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. In addition, Fusion is pursuing combination programs between RCs and DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radiopharmaceutical manufacturing facility to meet supply demand for Fusion's growing pipeline of RCs.

Fusion is seeking outstanding applicants for a Research & Development Laboratory Manager to support a broad range of preclinical development activities. This position is lab-based, and located in Hamilton, Ontario, Canada.

Responsibilities (including, but not limited to) :

• Oversight of the daily operations of the Biology, Imaging and Radiochemistry labs in the ILLF, as well as the Chemistry labs within Fusion's R&D Facilities.
• Evaluate, organize, plan, direct, the maintenance needs of the Fusion Research labs, including : equipment maintenance and servicing, waste disposal, laboratory safety related inspections, laboratory cleaning services.
• Maintain external relationships with key consumable vendors, service providers (example : biohazard, chemical waste disposal, LN2 supply and gas cylinder supply) and McMaster University CAF / AREB / Biosafety / Health Physics within the context and scope of enabling efficient operations of Fusions ILLF and animal facility.
• Support reagents and consumables ordering for the R&D Teams.
• Collaborate in cross-functional initiatives to help run the ILLF effectively and efficiently.
• Establish and maintain standardized processes, constantly review and implement new processes to drive continuous improvement in our operations.
• Participate in the implementation health and safety programs and activities such as training, communication, inspection, generation and review of safety SOPs and WIs, investigation and the promotion of general safety.
• Oversee and coordinate laboratory audits, safety compliance records, biological, chemical and radiological shipment / receiving paperwork, SDS / Biological, radiological and chemical inventories.
• Help coordinate shipments, deliveries and the scheduling of escorted maintenance personnel.
• Oversee daily delivery pick ups from main reception and the delivery to the appropriate lab / refrigerator / freezer or staff member.
• Escalate issues to upper management for support as required.
• Facilitate relationship building within the organization to improve lab initiatives.
• Manage a team of lab ops technicians who will support and execute on many of the above responsibilities.

Qualifications :

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.