At Roche / Genentech Pharma Product Development Global Clinical Operations (PDG), we are determined to transform drug development and realize our Pharma Ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2029. We are looking for a Clinical Operations Therapeutic Area Leader to lead and drive the delivery of our Oncology-Solid Tumors’ Portfolio. This senior people leadership position holds significant accountability for clinical operations strategy and execution as well as enterprise collaboration.

PD’s mission is to improve patients’ lives around the world through unique medicines that have a meaningful impact. Cross functionally we conduct global clinical trials, analyze results, monitor safety, and work with regulatory authorities to provide truly differentiated medicines to patients. Our primary therapeutic focus areas are Oncology, Hematology, Neurology, Immunology, Ophthalmology, Cardiovascular, Renal, and Metabolism. We attract, develop, and retain the most talented people in the industry, and have Development centers in Basel, Switzerland; South San Francisco, California; Welwyn Garden City, England; Mississauga, Canada; and Shanghai, China, as well as operations in many other countries.

The Opportunity :

The Oncology-Solid Tumors Clinical Operations Therapeutic Area Leader in PDG at Roche / Genentech is responsible and accountable for the strategy and delivery of the PD portfolio of programs and studies in Oncology-Solid Tumors. As the Oncology-Solid Tumors Therapeutic Area Leader, you will :

Develop and Refine Oncology-Solid Tumors Portfolio Strategy

Accountable for the overall PD clinical operations strategy for Oncology-Solid Tumors. Continuously adapt the strategy to the changing landscape to ensure alignment with the Clinical Development Plan (CDP) and the One Pharma Strategy.

Portfolio Oversight and Risk Management

Provide active oversight of asset and study delivery, maintaining awareness of portfolio status, identifying risks, and implementing mitigation strategies to ensure successful clinical trial execution.

Strategic Stakeholder Alignment and Decision-Making

Collaborate with cross-functional stakeholders, including PDG, APO, COEs, and enterprise teams, to drive alignment. Act as a key decision-maker for prioritizing and guiding strategic operational decisions for the Oncology-Solid Tumors portfolio.

Operational Leadership and Process Innovation

Leverage data analytics and portfolio optimization expertise to enhance speed, quality, efficiency, and budget management. Foster innovation by implementing new solutions and optimizing processes to improve probability of technical success (PTS) and patient-centered research.

Representation and Enterprise Influence

Serve as the PDG voice for Oncology-Solid Tumors within Roche, building collaborative relationships with internal leaders and external partners, including health authorities, patient advocacy organizations, Therapeutic Area Experts (TAEs), and vendors.

Leadership and Talent Development

Lead a matrixed organization of ~150 employees, including 10-12 direct reports. Foster a culture of collaboration, inclusivity, and high performance while championing diversity, equity, and inclusion (DE&I) to empower underrepresented voices and strengthen the talent pipeline.

Collective Leadership with an Enterprise Perspective

Represent Oncology-Solid Tumors as a member of the Portfolio Delivery Leadership Team. Provide collective leadership to align PDG and PD organizational priorities in service of patients, investigative sites, and Roche’s broader mission.

People Management and Administrative Responsibilities

Manage performance and growth through feedback, coaching, and development planning. Oversee administrative tasks related to team operations, such as Workday processes and employment matters, to ensure effective team management.

Who you are :

15+ years pharmaceutical clinical Operations experience with at least 10 years being in global clinical operations Strategy Leadership. Additional commercial or relevant experience is considered an asset.

Strong knowledge in the area of Oncology, including external trends and issues in the global Oncology-Solid Tumors landscape, and development and delivery of large endpoint-driven clinical trials

Comprehensive understanding of global Pharma Clinical development in international settings

Proven success in strategy development and execution using analytics, data-driven decision-making, and a track record of expanding access to underserved populations while meeting or exceeding ambitious goals.

Experience managing large, matrixed organizations, including leading direct reports and people leaders, recruiting and developing high-performing teams, and fostering collaboration and trust with stakeholders.

Fluency in English with additional language skills as an asset, and flexibility for frequent national or international travel based on business needs.

This position can be located at the Basel, Switzerland; South San Francisco, United States; Welwyn, England; or Mississauga, Canada HQ sites. Expectation of ongoing and sustained campus presence at the site in compliance with local requirements.

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $227,600 - $422,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.