Job descriptionThe Department of Clinical Neurosciences in the Cumming School of Medicine invites applications for a Clinical Research Informatics Specialist. This full‑time fixed‑term position is for approximately 1 year based on grant funding, with the possibility of extension. Reporting to the Manager, Data Science & Research Technology of the Calgary Stroke Program's Stroke Clinical Trials Group (SCTG), the incumbent will play a hybrid technical and operational role supporting the design, development, deployment, and day‑to‑day operation of the technical and data infrastructure that underpins the group’s clinical trials portfolio, Imaging Core Lab, and broader research operations.
The Clinical Research Informatics Specialist will leverage expertise in computer science, software development, data systems, cloud architecture, and clinical research informatics to build, maintain, and operate internal platforms, databases, pipelines, and integrations. The role also involves providing applied informatics and data operations support to active trials and the Imaging Core Lab, including eCRF and database builds in the group’s EDC, edit check and data validation logic, CDISC‑aligned variable mapping, eTMS study setup, data exports, operational reporting, DICOM data intake and QC, and site liaison for data and imaging issues.
Software Development Accountabilities
Design, develop, and maintain internal web applications, dashboards, and technical tools supporting SCTG trial operations, Imaging Core Lab workflows, financial tracking, contract tracking, and operational reporting.
Design and implement REST/GraphQL APIs, data models, and integrations between trial systems (eTMS, EDC, IxRS/IWRS, imaging platforms, finance systems, partner systems, and third‑party vendor tools).
Write clean, well‑documented, testable code following version control, code review, and release management practices appropriate for regulated research environments.
Maintain existing SCTG software assets, including bug fixes, feature enhancements, refactoring, and technology upgrades.
Evaluate and prototype new frameworks, libraries, and services to support evolving research requirements.
Cloud Infrastructure & Technical Operations Accountabilities
Architect, deploy, and maintain cloud infrastructure (AWS, Azure, or GCP) hosting SCTG research applications, databases, and data storage.
Administer authentication and access controls (SSO, OAuth, role‑based access) across SCTG platforms, aligned with institutional policies and research data governance requirements.
Implement infrastructure‑as‑code, containerization, CI/CD pipelines, logging, monitoring, alerting, and backup/disaster‑recovery processes.
Coordinate with University of Calgary IT, Alberta Health Services IT, and external vendors on network, security, privacy, and data‑sharing requirements.
Data Management and Quality Control Accountabilities
Design and maintain relational databases and data models supporting clinical trial operations, Imaging Core Lab activities, finance, HR, and operational analytics.
Build and maintain data pipelines and ETL/ELT workflows that ingest, transform, validate, and reconcile data across EDC systems, imaging platforms, finance exports, partner systems, and other data sources.
Develop automated data quality control, validation, and reconciliation routines, with exception reporting, audit trails, and traceability.
Support DICOM and imaging data handling workflows, including transfer, anonymization, metadata management, and long‑term storage.
Analysis, Scripting, and Automation Accountabilities
Develop Python, R, and SQL scripts, notebooks, and automated reports to support trial operations, safety monitoring, enrollment tracking, financial performance, imaging analytics, and other research reporting needs.
Automate recurring operational reports (e.g., DSMC safety summaries, enrollment dashboards, site performance, financial cashflow).
Collaborate with investigators, data scientists, and biostatisticians on analytical workflows, reproducible research pipelines, and supporting publications and regulatory submissions.
Clinical Trial Operations Support Accountabilities
Build, configure, and maintain study‑specific eCRFs and database builds in the group’s EDC platform, in collaboration with clinical research coordinators, data managers, and investigators.
Develop, implement, and maintain data edit specification plans, edit checks, range checks, skip logic, and cross‑form validation rules to enforce trial data quality at the point of entry.
Develop and maintain CDISC‑aligned variable naming conventions, SDTM/ADaM mapping, and controlled terminology for new and existing studies.
Configure and maintain new study setup within the group’s electronic Trial Master System (eTMS), including study structures, user access, document templates, and workflow configurations.
Imaging Core Lab Operations Support Accountabilities
Support day‑to‑day imaging data operations including intake, transfer, de‑identification, metadata extraction, QC, and labeling of DICOM datasets submitted by participating trial sites.
Act as a technical point of contact for trial sites and imaging technologists, liaising to troubleshoot imaging submission issues, missing data, protocol deviations, and quality flags.
Maintain imaging data catalogs, metadata systems, and tracking tools in coordination with the Imaging Core Lab team.
Support imaging workflow coordination, including reader assignments, read queues, and adjudication tracking where applicable.
Project Operations & Technical Support Accountabilities
Act as technical point of contact across SCTG projects for investigators, coordinators, imaging scientists, partners, and vendors.
Gather and document requirements, translate operational and scientific needs into technical specifications, and deliver fit‑for‑purpose solutions on schedule.
Provide technical input to trial protocols, case report forms, study manuals, data management plans, and vendor assessments where software, data, or infrastructure are involved.
Leadership & Collaboration Accountabilities
Provide technical mentorship and code review to students, trainees, and staff engaged in software or data work across SCTG and the Imaging Core Lab.
Manage competing technical priorities across multiple trials and projects, maintaining a transparent backlog and delivering reliably against agreed timelines.
Contribute to the strategic technical roadmap for SCTG infrastructure, informing build‑vs‑buy decisions, vendor selection, and platform choices.
Foster strong working relationships with principal investigators, clinical collaborators, industry and regulatory partners, and internal operations staff.
Qualifications / Requirements
BSc required; MSc or PhD preferred in Computer Science, Data Science, Health Informatics, Biomedical Informatics, or a related discipline.
3–7 years of professional experience in software development, data systems, or research informatics roles; experience in clinical research, healthcare, or regulated industries is strongly preferred.
Strong programming proficiency in Python (required) and at least one of JavaScript/TypeScript, R, Java, C#, or Go.
Demonstrated full‑stack web development experience (e.g., React/Vue, Node.js/Express, FastAPI/Django/Flask) and REST/GraphQL API design.
Solid experience with relational database design and SQL (PostgreSQL, MySQL, or equivalent); familiarity with NoSQL and document stores (MongoDB, Firestore) considered an asset.
Hands‑on experience with cloud infrastructure (AWS, Azure, or GCP), including compute, storage, networking, identity/access management, and basic infrastructure‑as‑code (Terraform, CloudFormation, or Bicep).
Experience with containerization (Docker) and common DevOps practices: CI/CD pipelines (GitHub Actions, GitLab CI), version control (Git/GitHub), code review, automated testing, and release management.
Experience building and maintaining data pipelines and ETL/ELT workflows, performing automated data quality control, and building reporting tools or dashboards (e.g., Power BI, Tableau, Metabase, or custom web dashboards).
Working knowledge of information security fundamentals, authentication and authorization patterns (OAuth, SSO, SAML), secrets management, logging, and monitoring.
Familiarity with clinical research data standards and trial systems (e.g., EDC platforms such as Medidata RAVE, Veeva Vault CDMS, REDCap, or Castor; eTMS platforms; CDISC standards including CDASH, SDTM, and ADaM; DICOM; HL7/FHIR; 21 CFR Part 11; ICH‑GCP; TCPS 2) is considered a strong asset; willingness to rapidly acquire domain knowledge in these areas is essential.
Demonstrated willingness and ability to operate in a hybrid technical and operational role, shifting fluidly between software/data development work and hands‑on support of trial and imaging operations as team priorities require.
Application Deadline: May 20, 2026
This position is part of the AUPE bargaining unit, and falls under the Technical Job Family, Phase 2.
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