Chief technology officer Jobs in Burlington, ON

OmniaBio : Site Head & Chief Technology Officer, Manufacturing Operations

Hamilton, ON, Canada

Job Description

Posted Friday, November 28, 2025 at 5 : 00 AM

About OmniaBio :

OmniaBio Inc. is a technology-driven, global CDMO specializing in cell and gene therapies, with a mission to transform biomanufacturing with AI and automation. Located at McMaster Innovation Park in Hamilton, Ontario, OmniaBio leverages over a decade of expertise in regenerative medicine and advanced therapies developed in partnership with CCRM. Committed to digital transformation, OmniaBio integrates automation, robotics, and artificial intelligence into its operations to drive efficiency, enhance quality, and increase throughput. This innovative approach supports end-to-end CDMO services—from development through GMP manufacturing and scale-up—helping clients accelerate the path to market for transformative treatments. OmniaBio focuses on immune cell-based therapies, induced pluripotent stem cell therapies, and lentiviral vectors, positioning itself as a leader in advancing and maturing cell and gene therapy manufacturing. With a strategic vision to meet the surging global demand, OmniaBio aims to enable broad access to cutting‑edge therapies worldwide. Visit www.omniabio.com to learn more.

Position Summary :

OmniaBio is seeking a Site Head & CTO, Manufacturing Operations to lead, from a manufacturing operations perspective, the transformation of its state‑of‑the‑art facility, completed in 2024. This leadership position will oversee key site functions to ensure the achievement of business goals, uphold quality and compliance standards, and fulfill client needs to supply safe, effective products to patients.

The ideal candidate will foster a culture of continuous improvement, safety, and energy, while maintaining high levels of customer satisfaction. This role demands a high level of leadership, strategic vision, and business acumen. The Site Head will play a critical role in shaping the organizational culture to deliver outstanding results across multiple advanced therapy platforms, while managing profit and loss to meet financial targets.

A key aspect of this role is the critical integration of cutting‑edge AI, automation, and robotics manufacturing technologies, including both software systems and task‑performing robotic systems. The Site Head will be responsible for driving the deployment and advancement of these digital and robotic systems, ensuring seamless operational integration, enhanced efficiency, and consistent quality in manufacturing processes.

Success in this role requires operational excellence across all site functions to meet strategic and operational objectives, alongside legal and administrative leadership responsibilities. The position requires a balanced approach to aligning client expectations with business needs.

The Site Head will have direct and matrix management responsibility for Manufacturing, Operations, Quality Control, Quality Assurance, Engineering, Facilities, EHS, Continuous Improvement, Compliance, Regulatory Affairs, Project Management Office (PMO), and Supply Chain activities. Reporting directly to the CEO, the successful candidate will collaborate closely with OmniaBio leadership and key stakeholders at the Centre for Commercialization of Regenerative Medicine (CCRM).

Key Responsibilities : Site Head

• Lead and oversee all operational activities across the entire batch production value chain, ensuring efficient, compliant, and high‑quality manufacturing of Cell and Gene Therapy products.
• Ensure that the facility, systems, and workforce are appropriately equipped, trained, and maintained to safely meet the demands of advanced biomanufacturing while adhering to the highest standards of safety, quality, and compliance.
• Collaborate with functional department leads to ensure full compliance with all applicable corporate, regulatory, and industry standards, including GMP, ISO, and other relevant guidelines.
• Drive site operations to achieve and exceed the company’s annual business goals, scaling capacity and capabilities in alignment with growth strategies.
• Ensure an exceptional customer experience by delivering on commitments, maintaining open communication through site visits, meetings, teleconferences, and timely, transparent correspondence.
• Take ownership of the site’s P&L, as applicable, including budget management, cost control, and financial performance to meet or surpass set targets.
• Build, develop, and retain high‑performing teams by fostering a positive employee relations environment, including recruiting top talent, setting performance standards, supporting career development, and implementing reward and recognition programs.
• Promote a culture of high performance, accountability, and engagement across all levels of the organization.
• Develop, monitor, and report on key operational performance metrics and KPIs that inform decision-making, identify areas for improvement, and track progress toward operational excellence.
• Cultivate a culture of continuous improvement by implementing lean practices, fostering innovation, and driving process optimizations to maximize efficiency, quality, and throughput.
• Ensure EH&S (Environmental, Health & Safety) performance is aligned with, or exceeds, industry best practices, maintaining top quartile rankings across relevant safety and environmental metrics.
• Lead digital transformation initiatives by integrating AI, automation, and robotics technologies into manufacturing processes, ensuring seamless operational integration, scalability, and compliance, thereby positioning the site as a leader in automated CGT production.
• Act as a strategic leader and influencer, representing the site within the organization, at industry forums, and with external partners, including regulatory authorities and the community.

Key Responsibilities : CTO, Manufacturing Operations

Leadership Qualifications :

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OmniaBio is a developing organization and represents a fluid working environment. Flexibility and adaptability are essential, and duties will be influenced by the needs of the organization.

Applicants must be legally eligible to work in Canada.

An applicant’s compensation package is finalized once the interview process is concluded and accounts for the nature of the role as well as the experience, competencies (job knowledge, skills and abilities) of the applicant and internal equity.

OmniaBio is committed to accessibility, diversity, and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process, providing the applicant has met the bona fide requirements for the open position. Applicants should make their requirements known once contacted to schedule an interview, or when the job offer has been made.

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